Drew Pardoll (Chairman), M.D., Ph.D.
Dr. Pardoll serves as the Abeloff Professorship of Oncology, Director of the Bloomberg-Kimmel Institute for Cancer Immunotherapy and Director of the Cancer Immunology Program at the Johns Hopkins School of Medicine. Over the past two decades, Dr. Pardoll has studied molecular aspects of dendritic cell biology and immune regulation, particularly related to mechanisms by which cancer cells evade elimination by the immune system. He is an inventor of several immunotherapies, including GVAX cancer vaccines and Listeria monocytogenes-based cancer vaccines. Dr. Pardoll is an author on over 200 peer-reviewed articles as well as more than 20 book chapters on T cell immunology and cancer vaccines. He has served on the editorial board of the Journal of the National Cancer Institute and Cancer Cell, and has served on the Scientific Advisory Boards for numerous academic and corporate institutions.
Thomas Gajewski, M.D., Ph.D.
Dr. Gajewski is the leader of the Immunology and Cancer program at the University of Chicago Comprehensive Cancer Center, Director of Melanoma Oncology, and a Professor in the Ben May Cancer Institute. His research interests include the role of the STING (Stimulator of Interferon Genes) pathway in immunity, the molecular and cellular regulation of T lymphocyte activation and differentiation, and the application of this information in immune-based cancer therapy. Dr. Gajewski has published more than 200 papers in peer-reviewed journals on basic aspects of T cell biology, anti-tumor immunity, and melanoma therapy. He was formerly President of the Society for Immunotherapy of Cancer, has served as an editor for Cancer Research and the Journal for Immunotherapy of Cancer and has received numerous awards and honors including the Burroughs Wellcome Fund Clinical Scientist Award for Translational Research and the American Cancer Society-Jules L. Plangere Jr. Family Foundation Professorship in Cancer Immunotherapy.
Darren Higgins, Ph.D.
Dr. Higgins is a professor of Microbiology and Immunobiology at Harvard Medical School. His laboratory focuses on understanding fundamental host-pathogen interactions that lead to virulence, and the development of protective immunity to intracellular pathogens. He serves as an editorial board member and reviewer for several prominent journals (Cell, Nature, PLoS Pathogens) and has led projects on antigen discovery and vaccine development for the New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases, Boston Children’s Hospital, and the Dana Farber Cancer Center. Dr. Higgins is an author on over 50 peer-reviewed articles, is an inventor on several patents and has received numerous awards and honors. He co-founded and served on the Scientific Advisory Board of Genocea Biosciences Inc.
F. Stephen Hodi, M.D.
Dr. Hodi is the Director of the Melanoma Center and the Center for Immuno-Oncology at Dana-Farber/Brigham and Women’s Cancer Center, the Sharon Crowley Martin Chair in Melanoma at Dana-Farber Cancer Institute and Professor of Medicine at Harvard Medical School. Dr. Hodi is an internationally recognized leader in the development of immune therapy and melanoma therapeutics. He is known for the clinical development of immune checkpoint inhibitors, and his clinical investigation efforts have pioneered the use of immune checkpoint blockade and combinatorial approaches to treat cancer. He is an author on over 100 peer-reviewed articles including publications in the Proceedings of the National Academy of Sciences, Journal of Clinical Oncology and the New England Journal of Medicine. He serves on the editorial board of several immunology and oncology journals and has received numerous awards and honors.
Frank McCormick, Ph.D., F.R.S., D.Sc.
Dr. McCormick participates in Aduro’s Scientific Advisory Board in his capacity as a member of the Science and Technology Committee of the board of directors. Dr. McCormick is Director of the University of California, San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center, and Associate Dean of the UCSF School of Medicine. He has been a Fellow of the Royal Society since 1996. Prior to joining the UCSF faculty, Dr. McCormick pursued cancer-related work with several biotechnology firms, including Cetus and Chiron Corporation. In addition, Dr. McCormick founded Onyx Pharmaceuticals and served as its Chief Scientific Officer until 1996.
Dr. Mekalanos is the Adele H. Lehman Professor of Microbiology and Immunobiology at Harvard Medical School. He has served as Chair of the Microbiology and Molecular Genetics Department since 1996, and he is a member of the National Academy of Sciences and the American Academy of Microbiology. His research investigates multiple facets of bacterial pathogenesis, with an emphasis on exploring virulence gene regulation and host-pathogen interactions. Recent awards include the Drexel Medicine Prize in Infectious Disease and the Sanofi-Institut Pasteur Award for Biomedical Research.
Wiebe Olijve, Ph.D.
Dr. Olijve is an experienced research leader. He came out of retirement to serve as CEO and co-founder of BioNovion (now Aduro Biotech Europe), a company focused on the development of B-select antibodies for the treatment of serious diseases. Prior to BioNovion, he was vice president of the Research Biologics Council at Schering-Plough Research Institute (now Merck Research Laboratories). Previously, he served as vice president and site head of Schering-Plough Biopharma. Prior to Schering-Plough, he spent over 30 years in leadership positions at Organon Research pioneering new programs and initiating genomics and bioinformatics for target identification, contributing to research advancement in both the Netherlands and the United States. He has served as a professor of Applied Biology at Radboud University, Nijmegen in the Netherlands since 1990. Dr. Olijve is an author on numerous publications.
Daniel A. Portnoy, Ph.D.
Dr. Portnoy is a Professor at the University of California, Berkeley with joint appointments in the Divisions of Biochemistry & Molecular Biology, Immunology and Pathogenesis, Infectious Diseases, and Microbial Biology. He holds the Edward E. Penhoet Distinguished Chair in Global Public Health and Infectious Diseases. Dr. Portnoy has focused his entire career of 30 years on the microbiology and immunology of Listeria monocytogenes. He is an expert on L. monocytogenes genetics, cell biology, and immunobiology and his lab was instrumental in the development of L. monocytogenes as a vector for cancer vaccines. He is an author on over 100 peer-reviewed articles in the areas of microbial pathogenesis, has served on the editorial board for numerous peer-reviewed journals and has received numerous awards and honors in the fields of microbiology and immunology. In April 2013, Dr. Portnoy was elected into the National Academy of Sciences.
David H. Raulet, Ph.D.
Dr. Raulet is a tumor immunologist who holds the Esther and Wendy Schekman Chair in Basic Cancer Biology, and is a Professor of Immunology and Pathogenesis in the department of Molecular and Cell Biology at the University of California, Berkeley. His research primarily addresses the specificity and function of innate lymphocytes such as natural killer (NK) cells, and T cells. His efforts focus on mechanisms of tumor immune-surveillance and approaches for immunotherapy of cancer. Over a period of 33 years, he has played a significant role in defining inhibitory and activating receptors on NK cells and mechanisms of tumor recognition mediated by these receptors, and the roles of these receptors in tumor immune-surveillance. He is an author on over 200 peer-reviewed articles, has served on the editorial board for numerous immunology and oncology journals and has received numerous awards and honors.
Stephen A. Sherwin, M.D.
Dr. Sherwin participates in Aduro’s Scientific Advisory Board in his capacity as a member of the Science and Technology Committee of the board of directors. Dr. Sherwin currently divides his time between advisory work in the life science industry and patient care and teaching in his specialty of medical oncology. He is a Clinical Professor of Medicine at the University of California, San Francisco, and a volunteer Attending Physician in Hematology-Oncology at the Zuckerberg San Francisco General Hospital. In addition to his advisory work with Aduro, Dr. Sherwin serves as a director of Biogen, Neurocrine Biosciences, and Rigel Pharmaceuticals and as a venture partner at Third Rock Ventures. He is also a member of the scientific steering committee of the Parker Institute for Cancer Immunotherapy. Dr. Sherwin holds a B.A. in Biology from Yale University, where he graduated summa cum laude, and an M.D. from Harvard Medical School. He is board-certified in internal medicine and medical oncology and a fellow of the American College of Physicians.